СAPSULAR ANTIGEN OF YERSINIA PESTIS

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Transcriptional analysis of the Yersinia pestis pH 6 antigen gene.

The pH 6 antigen of Yersinia pestis is a virulence protein whose gene, psaA, is positively regulated at the transcriptional level by low pH, mammalian temperature, and an upstream locus, psaE. Low pH appears to be required for initial psaA transcription, although increased temperature is necessary for full expression of the gene. In addition, psaA is monocistronic and its transcript has a relat...

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yersinia pestis which is the causative agent of pneumonic plague and distributed in all continents has led to many deaths during the history. because of its high mortality rate, it must be diagnosed and treated at the earliest time post infection and therefore, rapid diagnostic tests are required. in the present study, we cloned the coding sequence of f1 capsular antigen of the bacteria in the ...

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ژورنال

عنوان ژورنال: Russian Journal of Infection and Immunity

سال: 2015

ISSN: 2313-7398,2220-7619

DOI: 10.15789/2220-7619-2015-3-201-218